If a master sends an acknowledge message to multiple slaves (all on the same channel), they will all ack back simultaneously and the transmissions may collide. It is not possible for the master to tell them apart, and for that reason it is not recommended to use acknowledged messages in the forward direction when connecting to multiple slaves.
A shared channel does allow sending ack messages to multiple slaves on the same channel, as they will only send the ack back when addressed directly (i.e, the master would need to send a message to each sequentially).